Beyond Cell Penetrating Peptides: Designed Molecular Transporters

Por Wender, Paul A., Cooley, Christina B., Geihe, Erika I.
Publicado em 2012

Broadly Applicable Methodology for the Rapid and Dosable Small Molecule-Mediated Regulation of Transcription Factors in Human Cells

Por Shoulders, Matthew D., Ryno, Lisa M., Cooley, Christina B., Kelly, Jeffery W., Wiseman, R. Luke
Publicado em 2013

Fluorogenic atom transfer radical polymerization in aqueous media as a strategy for detection

Por Allen, Zachary T., Sackey-Addo, Jemima R., Hopps, Madeline P., Tahseen, Danyal, Anderson, Joseph T., Graf, Tyler A., Cooley, Christina B.
Publicado no Chem Sci (2018)

Oligocarbonate Molecular Transporters: Oligomerization Based Syntheses and Cell Penetrating Studies

Por Cooley, Christina B., Trantow, Brian M., Nederberg, Fredrik, Kiesewetter, Matthew K., Hedrick, James L., Waymouth, Robert M., Wender, Paul A.
Publicado em 2009

Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain

Por Cooley, Christina B., Ryno, Lisa M., Plate, Lars, Morgan, Gareth J., Hulleman, John D., Kelly, Jeffery W., Wiseman, R. Luke
Publicado no Proc Natl Acad Sci U S A (2014)

Reactive Oxygen Species (ROS)-Activatable Prodrug for Selective Activation of ATF6 after Ischemia/Reperfusion Injury

Por Palmer, Jonathan E., Brietske, Breanna M., Bate, Tyler C., Blackwood, Erik A., Garg, Manasa, Glembotski, Christopher C., Cooley, Christina B.
Publicado no ACS Med Chem Lett (2019)

Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells

Por Geihe, Erika I., Cooley, Christina B., Simon, Jeff R., Kiesewetter, Matthew K., Edward, Justin A., Hickerson, Robyn P., Kaspar, Roger L., Hedrick, James L., Waymouth, Robert M., Wender, Paul A.
Publicado em 2012

Pharmacologic IRE1/XBP1s Activation Confers Targeted ER Proteostasis Reprogramming

Por Grandjean, Julia M.D., Madhavan, Aparajita, Cech, Lauren, Seguinot, Bryan O., Paxman, Ryan J., Smith, Emery, Scampavia, Louis, Powers, Evan T., Cooley, Christina B., Plate, Lars, Spicer, Timothy P., Kelly, Jeffery W., Wiseman, R. Luke
Publicado no Nat Chem Biol (2020)

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation

Por Plate, Lars, Cooley, Christina B, Chen, John J, Paxman, Ryan J, Gallagher, Ciara M, Madoux, Franck, Genereux, Joseph C, Dobbs, Wesley, Garza, Dan, Spicer, Timothy P, Scampavia, Louis, Brown, Steven J, Rosen, Hugh, Powers, Evan T, Walter, Peter, Hodder, Peter, Wiseman, R Luke, Kelly, Jeffery W
Publicado no eLife (2016)