DIFFERENTIAL TOLERANCE OF ‘PSEUDO-PATHOGENIC’ TRYPTOPHAN RESIDUES IN CALCIUM-BINDING EGF DOMAINS OF SHORT FIBULIN PROTEINS

gan Nguyen, Annie, Hulleman, John D.
Cyhoeddwyd yn Exp Eye Res (2014)

Evidence of Alternative Cystatin C Signal Sequence Cleavage Which Is Influenced by the A25T Polymorphism

gan Nguyen, Annie, Hulleman, John D.
Cyhoeddwyd yn PLoS One (2016)

Prospective Application of Activity-Based Proteomic Profiling in Vision Research-Potential Unique Insights into Ocular Protease Biology and Pathology

gan Peng, Hui, Hulleman, John D.
Cyhoeddwyd yn Int J Mol Sci (2019)

An inducible form of Nrf2 confers enhanced protection against acute oxidative stresses in RPE cells

gan Vu, Khiem T., Hulleman, John D.
Cyhoeddwyd yn Exp Eye Res (2017)

Protocol for Designing Small-Molecule-Regulated Destabilizing Domains for In Vitro Use

gan Ramadurgum, Prerana, Hulleman, John D.
Cyhoeddwyd yn STAR Protoc (2020)

Genetic ablation of N-linked glycosylation reveals two key folding pathways for R345W fibulin-3, a secreted protein associated with retinal degeneration

gan Hulleman, John D., Kelly, Jeffery W.
Cyhoeddwyd yn FASEB J (2015)

Conditional, Genetically Encoded, Small Molecule–Regulated Inhibition of NFκB Signaling in RPE Cells

gan Vu, Khiem T., Zhang, Fang, Hulleman, John D.
Cyhoeddwyd yn Invest Ophthalmol Vis Sci (2017)

Protocol for In Vivo Evaluation and Use of Destabilizing Domains in the Eye, Liver, and Beyond

gan Ramadurgum, Prerana, Daniel, Steffi, Hulleman, John D.
Cyhoeddwyd yn STAR Protoc (2020)

MAPPING WILD-TYPE AND R345W FIBULIN-3 INTRACELLULAR INTERACTOMES

gan Hulleman, John D., Genereux, Joseph C., Nguyen, Annie
Cyhoeddwyd yn Exp Eye Res (2016)

Translational attenuation differentially alters the fate of disease-associated fibulin proteins

gan Hulleman, John D., Balch, William E., Kelly, Jeffery W.
Cyhoeddwyd 2012

A Novel Luciferase Assay For Sensitively Monitoring Myocilin Variants in Cell Culture

gan Zadoo, Serena, Nguyen, Annie, Zode, Gulab, Hulleman, John D.
Cyhoeddwyd yn Invest Ophthalmol Vis Sci (2016)

Clinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization

gan Woodard, DaNae R., Nakahara, Emi, Hulleman, John D.
Cyhoeddwyd yn Sci Rep (2021)

Compromised mutant EFEMP1 secretion associated with macular dystrophy remedied by proteostasis network alteration

gan Hulleman, John D., Kaushal, Shalesh, Balch, William E., Kelly, Jeffery W.
Cyhoeddwyd 2011

A High-Throughput Cell-Based Gaussia Luciferase Reporter Assay for Identifying Modulators of Fibulin-3 Secretion

gan Hulleman, John D., Brown, Steven J., Rosen, Hugh, Kelly, Jeffery W.
Cyhoeddwyd yn J Biomol Screen (2012)

Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs’ Endothelial Corneal Dystrophy

gan Rong, Ziye, Gong, Xin, Hulleman, John D., Corey, David R., Mootha, V. Vinod
Cyhoeddwyd yn Transl Vis Sci Technol (2020)

Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity

gan Usui, Kenji, Hulleman, John D., Paulsson, Johan F., Siegel, Sarah J., Powers, Evan T., Kelly, Jeffery W.
Cyhoeddwyd 2009

ATF6 Activation Reduces the Secretion and Extracellular Aggregation of Destabilized Variants of an Amyloidogenic Protein

gan Chen, John J., Genereux, Joseph C., Qu, Song, Hulleman, John D., Shoulders, Matthew D., Wiseman, R. Luke
Cyhoeddwyd yn Chem Biol (2014)

Deducing the presence of proteins and proteoforms in quantitative proteomics

gan Bamberger, Casimir, Martínez-Bartolomé, Salvador, Montgomery, Miranda, Pankow, Sandra, Hulleman, John D., Kelly, Jeffery W., Yates, John R.
Cyhoeddwyd yn Nat Commun (2018)

A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye – Implications for Ocular Gene Therapy

gan Datta, Shyamtanu, Renwick, Marian, Chau, Viet Q., Zhang, Fang, Nettesheim, Emily R., Lipinski, Daniel M., Hulleman, John D.
Cyhoeddwyd yn Invest Ophthalmol Vis Sci (2018)

Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain

gan Cooley, Christina B., Ryno, Lisa M., Plate, Lars, Morgan, Gareth J., Hulleman, John D., Kelly, Jeffery W., Wiseman, R. Luke
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2014)