Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis

Tekijä Wender, Paul A.
Julkaistu 2013

Function Oriented Synthesis: Preparation and Initial Biological Evaluation of New A-Ring-Modified Bryologs

Tekijä Wender, Paul A., Reuber, Jenny
Julkaistu 2011

Improved Protein Kinase C Affinity through Final Step Diversification of a Simplified Salicylate-Derived Bryostatin Analog Scaffold

Tekijä Wender, Paul A., Staveness, Daryl
Julkaisussa Org Lett (2014)

The Design, Synthesis, and Evaluation of C7 Diversified Bryostatin Analogs Reveals a Hot Spot for PKC Affinity

Tekijä Wender, Paul A., Verma, Vishal A.
Julkaistu 2008

Apoptolidins E and F, New Glycosylated Macrolactones Isolated from Nocardiopsis sp

Tekijä Wender, Paul A., Longcore, Kate E.
Julkaistu 2009

Synthesis at the molecular frontier

Tekijä Wender, Paul A., Miller, Benjamin L.
Julkaistu 2009

Total Synthesis of Bryostatin 9

Tekijä Wender, Paul A., Schrier, Adam J.
Julkaistu 2011

Lead Diversification through a Prins-Driven Macrocyclization Strategy: Application to C13-Diversified Bryostatin Analogues

Tekijä Wender, Paul A., Billingsley, Kelvin L.
Julkaistu 2013

Apoptolidins B and C: Isolation, Structure Determination, and Biological Activity

Tekijä Wender, Paul A., Sukopp, Martin, Longcore, Kate
Julkaistu 2005

Tetramethyleneethane Equivalents: Recursive Reagents for Serialized Cycloadditions

Tekijä Wender, Paul A., Jeffreys, Matthew S., Raub, Andrew G.
Julkaisussa J Am Chem Soc (2015)

Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes

Tekijä Ryckbosch, Steven M., Wender, Paul A., Pande, Vijay S.
Julkaisussa Nat Commun (2017)

Practical Synthesis of Prostratin, DPP, and Their Analogs, Adjuvant Leads Against Latent HIV

Tekijä Wender, Paul A., Kee, Jung-Min, Warrington, Jeffrey M.
Julkaistu 2008

Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis

Tekijä Wender, Paul A., Loy, Brian A., Schrier, Adam J.
Julkaistu 2011

Beyond Cell Penetrating Peptides: Designed Molecular Transporters

Tekijä Wender, Paul A., Cooley, Christina B., Geihe, Erika I.
Julkaistu 2012

Function through Synthesis-Informed Design

Tekijä Wender, Paul A., Quiroz, Ryan V., Stevens, Matthew C.
Julkaisussa Acc Chem Res (2015)

Studies on the regio- and diastereo-selective epoxidation of daphnanes and tiglianes

Tekijä Boudreault, Pierre-Luc, Mattler, Jennifer K., Wender, Paul A.
Julkaisussa Tetrahedron Lett (2015)

Bryostatin and its synthetic analog, picolog rescue dermal fibroblasts from prolonged stress and contribute to survival and rejuvenation of human skin equivalents

Tekijä Khan, Tapan K., Wender, Paul A., Alkon, Daniel L.
Julkaisussa J Cell Physiol (2017)

Efficient Synthetic Access to a New Family of Highly Potent Bryostatin Analogues via a Prins-Driven Macrocyclization Strategy

Tekijä Wender, Paul A., DeChristopher, Brian A., Schrier, Adam J.
Julkaistu 2008

Propargyltrimethylsilanes as Allene Equivalents in Transition Metal-Catalyzed [5 + 2] Cycloadditions

Tekijä Wender, Paul A., Inagaki, Fuyuhiko, Pfaffenbach, Magnus, Stevens, Matthew C.
Julkaistu 2014

Computer-Guided Design, Synthesis, and Protein Kinase C Affinity of a New Salicylate-Based Class of Bryostatin Analogs

Tekijä Wender, Paul A., Nakagawa, Yu, Near, Katherine E., Staveness, Daryl
Julkaisussa Org Lett (2014)