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Total Synthesis of Bryostatin 9
The total synthesis of bryostatin 9 was accomplished using a uniquely step economical and convergent Prins-driven macrocyclization strategy. At 25 linear and 42 total steps, this is currently the most concise and convergent (5 steps post fragment coupling) synthesis of a potent bryostatin.
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129979/ https://ncbi.nlm.nih.gov/pubmed/21618969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja203034k |
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