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Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis

We review in part our computational, design, synthesis, and biological studies on a remarkable class of compounds and their designed analogs that have led to preclinical candidates for the treatment of cancer, a first-in-class approach to Alzheimer's disease, and a promising strategy to eradica...

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Autors principals: Wender, Paul A., Loy, Brian A., Schrier, Adam J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364006/
https://ncbi.nlm.nih.gov/pubmed/22661768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201100020
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