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Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity
Modern methods for the identification of therapeutic leads include chemical or virtual screening of compound libraries. Nature’s library represents a vast and diverse source of leads, often exhibiting exquisite biological activities. However, the advancement of natural product leads into the clinic...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084132/ https://ncbi.nlm.nih.gov/pubmed/21415363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015270108 |
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