Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents

HIV latency in resting CD4+ T cell represents a key barrier preventing cure of the infection with antiretroviral drugs alone. Latency reversing agents (LRAs) can activate HIV expression in latently infected cells, potentially leading to their elimination through virus-mediated cytopathic effects, ho...

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Publicado no:Virology
Main Authors: Marsden, Matthew D., Wu, Xiaomeng, Navab, Sara M., Loy, Brian A., Schrier, Adam J., DeChristopher, Brian A., Shimizu, Akira J., Hardman, Clayton T., Ho, Stephen, Ramirez, Christina M., Wender, Paul A., Zack, Jerome A.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018613/
https://ncbi.nlm.nih.gov/pubmed/29800728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.05.006
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