Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents

HIV latency in resting CD4+ T cell represents a key barrier preventing cure of the infection with antiretroviral drugs alone. Latency reversing agents (LRAs) can activate HIV expression in latently infected cells, potentially leading to their elimination through virus-mediated cytopathic effects, ho...

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Vydáno v:Virology
Hlavní autoři: Marsden, Matthew D., Wu, Xiaomeng, Navab, Sara M., Loy, Brian A., Schrier, Adam J., DeChristopher, Brian A., Shimizu, Akira J., Hardman, Clayton T., Ho, Stephen, Ramirez, Christina M., Wender, Paul A., Zack, Jerome A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Academic Press 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018613/
https://ncbi.nlm.nih.gov/pubmed/29800728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.05.006
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