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Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents

HIV latency in resting CD4+ T cell represents a key barrier preventing cure of the infection with antiretroviral drugs alone. Latency reversing agents (LRAs) can activate HIV expression in latently infected cells, potentially leading to their elimination through virus-mediated cytopathic effects, ho...

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Dades bibliogràfiques
Publicat a:Virology
Autors principals: Marsden, Matthew D., Wu, Xiaomeng, Navab, Sara M., Loy, Brian A., Schrier, Adam J., DeChristopher, Brian A., Shimizu, Akira J., Hardman, Clayton T., Ho, Stephen, Ramirez, Christina M., Wender, Paul A., Zack, Jerome A.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018613/
https://ncbi.nlm.nih.gov/pubmed/29800728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.05.006
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