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Function Oriented Synthesis: Preparation and Initial Biological Evaluation of New A-Ring-Modified Bryologs

The synthesis and biological evaluation of the first members of a new series of designed bryostatin A-ring analogues (bryologs) are described. An advanced intermediate is produced that allows for step economical access to diverse analogs. The first of these analogues, bearing side chains of complete...

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Detalhes bibliográficos
Main Authors: Wender, Paul A., Reuber, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254100/
https://ncbi.nlm.nih.gov/pubmed/22247574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2011.09.058
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