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Apoptolidins B and C: Isolation, Structure Determination, and Biological Activity

[Figure: see text] Apoptolidin (1) is a promising new therapeutic lead that exhibits remarkable selectivity against cancer cells relative to normal cells. We report the isolation, characterization, solution structure, stability, and biological activity of two new members of this family: apoptolidins...

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Bibliographic Details
Main Authors: Wender, Paul A., Sukopp, Martin, Longcore, Kate
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533581/
https://ncbi.nlm.nih.gov/pubmed/15987196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol051074o
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