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Apoptolidins B and C: Isolation, Structure Determination, and Biological Activity

[Figure: see text] Apoptolidin (1) is a promising new therapeutic lead that exhibits remarkable selectivity against cancer cells relative to normal cells. We report the isolation, characterization, solution structure, stability, and biological activity of two new members of this family: apoptolidins...

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Detalhes bibliográficos
Main Authors: Wender, Paul A., Sukopp, Martin, Longcore, Kate
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533581/
https://ncbi.nlm.nih.gov/pubmed/15987196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol051074o
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