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Correlation of F(0)F(1)-ATPase Inhibition and Antiproliferative Activity of Apoptolidin Analogs
[Figure: see text] Apoptolidin (1) exhibits potent and highly selective apoptosis inducing activity against sensitive cancer cell lines and is hypothesized to act by inhibition of mitochondrial F(0)F(1)-ATP synthase. A series of apoptolidin derivatives, including a new intermolecular Diels-Alder add...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533578/ https://ncbi.nlm.nih.gov/pubmed/16468718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol052800q |
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