An Endogenous Serine/Threonine Protein Phosphatase Inhibitor, G-Substrate, Reduces Vulnerability in Models of Parkinson's Disease

by Chung, Chee Yeun, Koprich, James B., Endo, Shogo, Isacson, Ole
Published 2007

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy

by Chung, Chee Yeun, Koprich, James B., Siddiqi, Hasan, Isacson, Ole
Published 2009

Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression

by Chung, Chee Yeun, Koprich, James B., Hallett, Penelope J., Isacson, Ole
Published 2009

The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration

by Deleidi, Michela, Hallett, Penelope J., Koprich, James B., Chung, Chee-Yeun, Isacson, Ole
Published 2010

Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection

by Chung, Chee Yeun, Seo, Hyemyung, Sonntag, Kai Christian, Brooks, Andrew, Lin, Ling, Isacson, Ole
Published 2005

SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones

by Donmez, Gizem, Arun, Anirudh, Chung, Chee-Yeun, McLean, Pamela J., Lindquist, Susan, Guarente, Leonard
Published 2012

High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life

by Lin, Zhicheng, Zhao, Ying, Chung, Chee Yeun, Zhou, Yanhong, Xiong, Nian, Glatt, Charles E., Isacson, Ole
Published 2010

The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons

by Chung, Chee Yeun, Licznerski, Pawel, Alavian, Kambiz N., Simeone, Antonio, Lin, Zhicheng, Martin, Eden, Vance, Jeffery, Isacson, Ole
Published 2010

FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome

by Caraveo, Gabriela, Soste, Martin, Cappelleti, Valentina, Fanning, Saranna, van Rossum, Damian B., Whitesell, Luke, Huang, Yanmei, Chung, Chee Yeun, Baru, Valeriya, Zaichick, Sofia, Picotti, Paola, Lindquist, Susan
Published in Proc Natl Acad Sci U S A (2017)

Functional integration of dopaminergic neurons directly converted from mouse fibroblasts

by Kim, Jongpil, Su, Susan C., Wang, Haoyi, Cheng, Albert W., Cassady, John P., Lodato, Michael A., Lengner, Christopher J., Chung, Chee-Yeun, Dawlaty, Meelad M., Tsai, Li-Huei, Jaenisch, Rudolf
Published 2011

In situ peroxidase labeling and mass-spectrometry connects alpha-synuclein directly to endocytic trafficking and mRNA metabolism in neurons

by Chung, Chee Yeun, Khurana, Vikram, Yi, Song, Sahni, Nidhi, Loh, Ken H., Auluck, Pavan K., Baru, Valeriya, Udeshi, Namrata D., Freyzon, Yelena, Carr, Steven A., Hill, David E., Vidal, Marc, Ting, Alice Y., Lindquist, Susan
Published in Cell Syst (2017)

Calcineurin determines toxic versus beneficial responses to α-synuclein

by Caraveo, Gabriela, Auluck, Pavan K., Whitesell, Luke, Chung, Chee Yeun, Baru, Valeriya, Mosharov, Eugene V., Yan, Xiaohui, Ben-Johny, Manu, Soste, Martin, Picotti, Paola, Kim, Hanna, Caldwell, Kim A., Caldwell, Guy A., Sulzer, David, Yue, David T., Lindquist, Susan
Published 2014

Yeast reveal a “druggable” Rsp5/Nedd4 Network that Ameliorates α–Synuclein Toxicity in Neurons

by Tardiff, Daniel F., Jui, Nathan T., Khurana, Vikram, Tambe, Mitali A., Thompson, Michelle L., Chung, Chee Yeun, Kamadurai, Hari B., Kim, Hyoung Tae, Lancaster, Alex K., Caldwell, Kim A., Caldwell, Guy A., Rochet, Jean-Christophe, Buchwald, Stephen L., Lindquist, Susan
Published 2013

Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient-Derived Neurons

by Chung, Chee Yeun, Khurana, Vikram, Auluck, Pavan K., Tardiff, Daniel F., Mazzulli, Joseph R., Soldner, Frank, Baru, Valeriya, Lou, Yali, Freyzon, Yelena, Cho, Sukhee, Mungenast, Alison E., Muffat, Julien, Mitalipova, Maisam, Pluth, Michael D, Jui, Nathan T., Schüle, Birgitt, Lippard, Stephen J., Tsai, Li-Huei, Krainc, Dimitri, Buchwald, Stephen L., Jaenisch, Rudolf, Lindquist, Susan
Published 2013

Functional Links Between Aβ Toxicity, Endocytic Trafficking and Alzheimer’s Disease Risk Factors in Yeast

by Treusch, Sebastian, Hamamichi, Shusei, Goodman, Jessica L., Matlack, Kent E.S., Chung, Chee Yeun, Baru, Valeriya, Shulman, Joshua M., Parrado, Antonio, Bevis, Brooke J., Valastyan, Julie S., Han, Haesun, Lindhagen-Persson, Malin, Reiman, Eric M., Evans, Denis A., Bennett, David A., Olofsson, Anders, DeJager, Philip L., Tanzi, Rudolph E., Caldwell, Kim A., Caldwell, Guy A., Lindquist, Susan
Published 2011

Genome-scale networks link neurodegenerative disease genes to alpha-synuclein through specific molecular pathways

by Khurana, Vikram, Peng, Jian, Chung, Chee Yeun, Auluck, Pavan K., Fanning, Saranna, Tardiff, Daniel F., Bartels, Theresa, Koeva, Martina, Eichhorn, Stephen W., Benyamini, Hadar, Lou, Yali, Nutter-Upham, Andy, Baru, Valeriya, Freyzon, Yelena, Tuncbag, Nurcan, Costanzo, Michael, Luis, Bryan-Joseph San, Schöndorf, David C., Barrasa, M. Inmaculada, Ehsani, Sepehr, Sanjana, Neville, Zhong, Quan, Gasser, Thomas, Bartel, David P., Vidal, Marc, Deleidi, Michela, Boone, Charles, Fraenkel, Ernest, Berger, Bonnie, Lindquist, Susan
Published in Cell Syst (2017)