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Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression

In Parkinson's disease (PD), dopaminergic (DA) neurons in the substantia nigra (SN, A9) are particularly vulnerable, compared to adjacent DA neurons within the ventral tegmental area (VTA, A10). Here, we show that in rat and human, one RAB3 isoform, RAB3B, has higher expression levels in A10 co...

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Hlavní autoři: Chung, Chee Yeun, Koprich, James B., Hallett, Penelope J., Isacson, Ole
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791667/
https://ncbi.nlm.nih.gov/pubmed/20007772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912193106
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