Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance

Por Chandarana, Keval, Gelegen, Cigdem, Irvine, Elaine E., Choudhury, Agharul I., Amouyal, Chloé, Andreelli, Fabrizio, Withers, Dominic J., Batterham, Rachel L.
Publicado em 2013

Diet and Gastrointestinal Bypass–Induced Weight Loss: The Roles of Ghrelin and Peptide YY

Por Chandarana, Keval, Gelegen, Cigdem, Karra, Efthimia, Choudhury, Agharul I., Drew, Megan E., Fauveau, Veronique, Viollet, Benoit, Andreelli, Fabrizio, Withers, Dominic J., Batterham, Rachel L.
Publicado em 2011

Brain Deletion of Insulin Receptor Substrate 2 Disrupts Hippocampal Synaptic Plasticity and Metaplasticity

Por Costello, Derek A., Claret, Marc, Al-Qassab, Hind, Plattner, Florian, Irvine, Elaine E., Choudhury, Agharul I., Giese, K. Peter, Withers, Dominic J., Pedarzani, Paola
Publicado em 2012

Differential Pre-mRNA Splicing Regulates Nnat Isoforms in the Hypothalamus after Gastric Bypass Surgery in Mice

Por Scott, William R., Gelegen, Cigdem, Chandarana, Keval, Karra, Efthimia, Yousseif, Ahmed, Amouyal, Chloé, Choudhury, Agharul I., Andreelli, Fabrizio, Withers, Dominic J., Batterham, Rachel L.
Publicado em 2013

Insulin receptor substrate 2 is a negative regulator of memory formation

Por Irvine, Elaine E., Drinkwater, Laura, Radwanska, Kasia, Al-Qassab, Hind, Smith, Mark A., O’Brien, Melissa, Kielar, Catherine, Choudhury, Agharul I, Krauss, Stefan, Cooper, Jonathan D., Withers, Dominic J., Giese, K. Peter
Publicado no Learn Mem (2011)

Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice

Por Smith, Mark A., Katsouri, Loukia, Irvine, Elaine E., Hankir, Mohammed K., Pedroni, Silvia M.A., Voshol, Peter J., Gordon, Matthew W., Choudhury, Agharul I., Woods, Angela, Vidal-Puig, Antonio, Carling, David, Withers, Dominic J.
Publicado no Cell Rep (2015)

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

Por Killick, Richard, Scales, Georgie, Leroy, Karelle, Causevic, Mirsada, Hooper, Claudie, Irvine, Elaine E., Choudhury, Agharul I, Drinkwater, Laura, Kerr, Fiona, Al-Qassab, Hind, Stephenson, John, Yilmaz, Zehra, Giese, K. Peter, Brion, Jean-Pierre, Withers, Dominic J., Lovestone, Simon
Publicado em 2009

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Por Claret, Marc, Smith, Mark A., Batterham, Rachel L., Selman, Colin, Choudhury, Agharul I., Fryer, Lee G.D., Clements, Melanie, Al-Qassab, Hind, Heffron, Helen, Xu, Allison W., Speakman, John R., Barsh, Gregory S., Viollet, Benoit, Vaulont, Sophie, Ashford, Michael L.J., Carling, David, Withers, Dominic J.
Publicado em 2007

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

Por Al-Qassab, Hind, Smith, Mark A., Irvine, Elaine E., Guillermet-Guibert, Julie, Claret, Marc, Choudhury, Agharul I., Selman, Colin, Piipari, Kaisa, Clements, Melanie, Lingard, Steven, Chandarana, Keval, Bell, Jimmy D., Barsh, Gregory S., Smith, Andrew J.H., Batterham, Rachel L., Ashford, Michael L.J., Vanhaesebroeck, Bart, Withers, Dominic J.
Publicado em 2009

The role of insulin receptor substrate 2 in hypothalamic and β cell function

Por Choudhury, Agharul I., Heffron, Helen, Smith, Mark A., Al-Qassab, Hind, Xu, Allison W., Selman, Colin, Simmgen, Marcus, Clements, Melanie, Claret, Marc, MacColl, Gavin, Bedford, David C., Hisadome, Kazunari, Diakonov, Ivan, Moosajee, Vazira, Bell, Jimmy D., Speakman, John R., Batterham, Rachel L., Barsh, Gregory S., Ashford, Michael L.J., Withers, Dominic J.
Publicado em 2005

Ribosomal protein S6 kinase 1 signaling regulates mammalian lifespan

Por Selman, Colin, Tullet, Jennifer M.A., Wieser, Daniela, Irvine, Elaine, Lingard, Steven J., Choudhury, Agharul I., Claret, Marc, Al-Qassab, Hind, Carmignac, Danielle, Ramadani, Faruk, Woods, Angela, Robinson, Iain C.A., Schuster, Eugene, Batterham, Rachel L., Kozma, Sara C., Thomas, George, Carling, David, Okkenhaug, Klaus, Thornton, Janet M., Partridge, Linda, Gems, David, Withers, Dominic J.
Publicado no Science (2009)

A link between FTO, ghrelin, and impaired brain food-cue responsivity

Por Karra, Efthimia, O’Daly, Owen G., Choudhury, Agharul I., Yousseif, Ahmed, Millership, Steven, Neary, Marianne T., Scott, William R., Chandarana, Keval, Manning, Sean, Hess, Martin E., Iwakura, Hiroshi, Akamizu, Takashi, Millet, Queensta, Gelegen, Cigdem, Drew, Megan E., Rahman, Sofia, Emmanuel, Julian J., Williams, Steven C.R., Rüther, Ulrich U., Brüning, Jens C., Withers, Dominic J., Zelaya, Fernando O., Batterham, Rachel L.
Publicado em 2013