The GSK3 hypothesis of Alzheimer's disease

Por Hooper, Claudie, Killick, Richard, Lovestone, Simon
Publicado em 2008

Transcription-based drug repurposing for COVID-19

Por Killick, Richard, Ballard, Clive, Doherty, Patrick, Williams, Gareth
Publicado no Virus Res (2020)

The Notch-1 intracellular domain is found in sub-nuclear bodies in SH-SY5Y neuroblastomas and in primary cortical neurons

Por Hooper, Claudie, Chapple, J. Paul, Lovestone, Simon, Killick, Richard
Publicado em 2007

p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

Por Hooper, Claudie, Meimaridou, Eirini, Tavassoli, Mahvash, Melino, Gerry, Lovestone, Simon, Killick, Richard
Publicado em 2007

Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or apoptin

Por Klanrit, Poramaporn, Flinterman, Marcella B., Odell, Edward W., Melino, Gerry, Killick, Richard, Norris, James S., Tavassoli, Mahvash
Publicado em 2007

Wnt3a induces exosome secretion from primary cultured rat microglia

Por Hooper, Claudie, Sainz-Fuertes, Ricardo, Lynham, Steven, Hye, Abdul, Killick, Richard, Warley, Alice, Bolondi, Cecilia, Pocock, Jennifer, Lovestone, Simon
Publicado em 2012

Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

Por Hill, Matthew J., Killick, Richard, Navarrete, Katherinne, Maruszak, Aleksandra, McLaughlin, Gemma M., Williams, Brenda P., Bray, Nicholas J.
Publicado no J Psychiatry Neurosci (2017)

Correction to: Wnt3a induces exosome secretion from primary cultured rat microglia

Por Hooper, Claudie, Sainz-Fuertes, Ricardo, Lynham, Steven, Hye, Abdul, Killick, Richard, Warley, Alice, Bolondi, Cecilia, Pocock, Jennifer, Lovestone, Simon
Publicado no BMC Neurosci (2020)

Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease

Por Sofola, Oyinkan, Kerr, Fiona, Rogers, Iain, Killick, Richard, Augustin, Hrvoje, Gandy, Carina, Allen, Marcus J., Hardy, John, Lovestone, Simon, Partridge, Linda
Publicado em 2010

Correction: Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease

Por Sofola, Oyinkan, Kerr, Fiona, Rogers, Iain, Killick, Richard, Augustin, Hrvoje, Gandy, Carina, Allen, Marcus J., Hardy, John, Lovestone, Simon, Partridge, Linda
Publicado em 2012

In vivo multi-parametric manganese-enhanced MRI for detecting amyloid plaques in rodent models of Alzheimer’s disease

Por Kim, Eugene, Di Censo, Davide, Baraldo, Mattia, Simmons, Camilla, Rosa, Ilaria, Randall, Karen, Ballard, Clive, Dickie, Ben R., Williams, Steven C. R., Killick, Richard, Cash, Diana
Publicado no Sci Rep (2021)

Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

Por Agostini, Massimiliano, Tucci, Paola, Killick, Richard, Candi, Eleonora, Sayan, Berna S., Rivetti di val Cervo, Pia, Nicotera, Pierluigi, McKeon, Frank, Knight, Richard A., Mak, Tak W., Melino, Gerry
Publicado em 2011

Prostate-derived Sterile 20-like Kinases (PSKs/TAOKs) Phosphorylate Tau Protein and Are Activated in Tangle-bearing Neurons in Alzheimer Disease

Por Tavares, Ignatius A., Touma, Dona, Lynham, Steven, Troakes, Claire, Schober, Megan, Causevic, Mirsada, Garg, Ritu, Noble, Wendy, Killick, Richard, Bodi, Istvan, Hanger, Diane P., Morris, Jonathan D. H.
Publicado em 2013

A role for APP in Wnt signalling links synapse loss with β-amyloid production

Por Elliott, Christina, Rojo, Ana I., Ribe, Elena, Broadstock, Martin, Xia, Weiming, Morin, Peter, Semenov, Mikhail, Baillie, George, Cuadrado, Antonio, Al-Shawi, Raya, Ballard, Clive G., Simons, Paul, Killick, Richard
Publicado no Transl Psychiatry (2018)

An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum

Por Ludtmann, Marthe H. R., Otto, Grant P., Schilde, Christina, Chen, Zhi-Hui, Allan, Claire Y., Brace, Selina, Beesley, Philip W., Kimmel, Alan R., Fisher, Paul, Killick, Richard, Williams, Robin S. B.
Publicado em 2014

Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release

Por Glennon, Elizabeth B, Lau, Dawn H W, Gabriele, Rebecca M C, Taylor, Matthew F, Troakes, Claire, Opie-Martin, Sarah, Elliott, Christina, Killick, Richard, Hanger, Diane P, Perez-Nievas, Beatriz G, Noble, Wendy
Publicado no Brain Commun (2020)

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus

Por Hamilton, Gillian, Killick, Richard, Lambert, Jean-Charles, Amouyel, Philippe, Carrasquillo, Minerva M., Pankratz, V. Shane, Graff-Radford, Neill R., Dickson, Dennis W., Petersen, Ronald C., Younkin, Steven G., Powell, John F., Wade-Martins, Richard
Publicado em 2012

p73: A Multifunctional Protein in Neurobiology

Por Killick, Richard, Niklison-Chirou, Maria, Tomasini, Richard, Bano, Daniele, Rufini, Alessandro, Grespi, Francesca, Velletri, Tania, Tucci, Paola, Sayan, Berna S., Conforti, Franco, Gallagher, Ewen, Nicotera, Pierluigi, Mak, Tak W., Melino, Gerry, Knight, Richard A, Agostini, Massimiliano
Publicado em 2011

Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease

Por Thambisetty, Madhav, Simmons, Andrew, Hye, Abdul, Campbell, James, Westman, Eric, Zhang, Yi, Wahlund, Lars-Olof, Kinsey, Anna, Causevic, Mirsada, Killick, Richard, Kloszewska, Iwona, Mecocci, Patrizia, Soininen, Hilkka, Tsolaki, Magda, Vellas, Bruno, Spenger, Christian, Lovestone, Simon
Publicado em 2011

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

Por Killick, Richard, Scales, Georgie, Leroy, Karelle, Causevic, Mirsada, Hooper, Claudie, Irvine, Elaine E., Choudhury, Agharul I, Drinkwater, Laura, Kerr, Fiona, Al-Qassab, Hind, Stephenson, John, Yilmaz, Zehra, Giese, K. Peter, Brion, Jean-Pierre, Withers, Dominic J., Lovestone, Simon
Publicado em 2009