Exon Skipping of Hepatic APOB Pre-mRNA With Splice-switching Oligonucleotides Reduces LDL Cholesterol In Vivo

Por Disterer, Petra, Al-Shawi, Raya, Ellmerich, Stephan, Waddington, Simon N, Owen, James S, Simons, J Paul, Khoo, Bernard
Publicado em 2013

Pharmacological removal of serum amyloid P component from intracerebral plaques and cerebrovascular Aβ amyloid deposits in vivo

Por Al-Shawi, Raya, Tennent, Glenys A., Millar, David J., Richard-Londt, Angela, Brandner, Sebastian, Werring, David J., Simons, J. Paul, Pepys, Mark B.
Publicado no Open Biol (2016)

Loss of phosphatidylinositol 4-kinase 2α activity causes late onset degeneration of spinal cord axons

Por Simons, J. Paul, Al-Shawi, Raya, Minogue, Shane, Waugh, Mark G., Wiedemann, Claudia, Evangelou, Stylianos, Loesch, Andrzej, Sihra, Talvinder S., King, Rosalind, Warner, Thomas T., Hsuan, J. Justin
Publicado em 2009

Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells

Por Lopes da Silva, Mafalda, O'Connor, Marie N., Kriston-Vizi, Janos, White, Ian J., Al-Shawi, Raya, Simons, J. Paul, Mössinger, Julia, Haucke, Volker, Cutler, Daniel F.
Publicado no J Cell Sci (2016)

Equilibrium contrast CMR for the detection of amyloidosis in mice

Por Moon James C, Pepys Mark B, Ordidge Roger J, Hawkins Philip N, Al-Shawi Raya, Simons Paul, Ellmerich Stephan, Price Anthony N, Campbell Adrienne E, Lythgoe Mark F
Publicado em 2011-02-01

Overexpression of 5-HT(2C) receptors in forebrain leads to elevated anxiety and hypoactivity

Por Kimura, Atsuko, Stevenson, Paula L, Carter, Roderick N, MacColl, Gavin, French, Karen L, Paul Simons, J, Al-Shawi, Raya, Kelly, Valerie, Chapman, Karen E, Holmes, Megan C
Publicado em 2009

Equilibrium contrast CMR for the detection of amyloidosis in mice

Por Campbell, Adrienne E, Price, Anthony N, Ellmerich, Stephan, Simons, Paul, Al-Shawi, Raya, Hawkins, Philip N, Ordidge, Roger J, Pepys, Mark B, Moon, James C, Lythgoe, Mark F
Publicado em 2011

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

Por Cooper, J Mark, Wiklander, PB Oscar, Nordin, Joel Z, Al-Shawi, Raya, Wood, Matthew J, Vithlani, Mansi, Schapira, Anthony H V, Simons, J Paul, El-Andaloussi, Samir, Alvarez-Erviti, Lydia
Publicado em 2014

C-reactive protein is essential for innate resistance to pneumococcal infection

Por Paul Simons, J, Loeffler, Jutta M, Al-Shawi, Raya, Ellmerich, Stephan, Hutchinson, Winston L, Tennent, Glenys A, Petrie, Aviva, Raynes, John G, de Souza, J Brian, Lawrence, Rachel A, Read, Kevin D, Pepys, Mark B
Publicado em 2014

Pathogenetic mechanisms of amyloid A amyloidosis

Por Simons, J. Paul, Al-Shawi, Raya, Ellmerich, Stephan, Speck, Ivana, Aslam, Samrina, Hutchinson, Winston L., Mangione, Palma P., Disterer, Petra, Gilbertson, Janet A., Hunt, Toby, Millar, David J., Minogue, Shane, Bodin, Karl, Pepys, Mark B., Hawkins, Philip N.
Publicado em 2013

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β(2)-Microglobulin

Por Halabelian, Levon, Ricagno, Stefano, Giorgetti, Sofia, Santambrogio, Carlo, Barbiroli, Alberto, Pellegrino, Sara, Achour, Adnane, Grandori, Rita, Marchese, Loredana, Raimondi, Sara, Mangione, P. Patrizia, Esposito, Gennaro, Al-Shawi, Raya, Simons, J. Paul, Speck, Ivana, Stoppini, Monica, Bolognesi, Martino, Bellotti, Vittorio
Publicado em 2014

Amyloid persistence in decellularized liver: biochemical and histopathological characterization

Por Mazza, Giuseppe, Simons, J. Paul, Al-Shawi, Raya, Ellmerich, Stephan, Urbani, Luca, Giorgetti, Sofia, Taylor, Graham W., Gilbertson, Janet A., Hall, Andrew R., Al-Akkad, Walid, Dhar, Dipok, Hawkins, Philip N., De Coppi, Paolo, Pinzani, Massimo, Bellotti, Vittorio, Mangione, P. Patrizia
Publicado no Amyloid (2016)

Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity

Por Woodhoo, Ashwin, Alonso, Maria B Duran, Droggiti, Anna, Turmaine, Mark, D'Antonio, Maurizio, Parkinson, David B, Wilton, Daniel K, Al-Shawi, Raya, Simons, Paul, Shen, Jie, Guillemot, Francois, Radtke, Freddy, Meijer, Dies, Feltri, M Laura, Wrabetz, Lawrence, Mirsky, Rhona, Jessen, Kristján R
Publicado em 2009

A specific nanobody prevents amyloidogenesis of D76N β(2)-microglobulin in vitro and modifies its tissue distribution in vivo

Por Raimondi, Sara, Porcari, Riccardo, Mangione, P. Patrizia, Verona, Guglielmo, Marcoux, Julien, Giorgetti, Sofia, Taylor, Graham W., Ellmerich, Stephan, Ballico, Maurizio, Zanini, Stefano, Pardon, Els, Al-Shawi, Raya, Simons, J. Paul, Corazza, Alessandra, Fogolari, Federico, Leri, Manuela, Stefani, Massimo, Bucciantini, Monica, Gillmore, Julian D., Hawkins, Philip N., Valli, Maurizia, Stoppini, Monica, Robinson, Carol V., Steyaert, Jan, Esposito, Gennaro, Bellotti, Vittorio
Publicado no Sci Rep (2017)