Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells

Weibel-Palade bodies (WPBs) are endothelial storage organelles that mediate the release of molecules involved in thrombosis, inflammation and angiogenesis, including the pro-thrombotic glycoprotein von Willebrand factor (VWF). Although many protein components required for WPB formation and function...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: Lopes da Silva, Mafalda, O'Connor, Marie N., Kriston-Vizi, Janos, White, Ian J., Al-Shawi, Raya, Simons, J. Paul, Mössinger, Julia, Haucke, Volker, Cutler, Daniel F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878995/
https://ncbi.nlm.nih.gov/pubmed/27068535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.187864
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