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Proximity proteomics of endothelial Weibel-Palade bodies identifies novel regulator of von Willebrand factor secretion

Weibel-Palade bodies (WPB) are unique secretory organelles of endothelial cells that store factors regulating vascular hemostasis and local inflammation. Endothelial activation triggers rapid exocytosis of WPB, leading to the surface presentation of adhesion molecules relevant for leukocyte rolling...

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發表在:Blood
Main Authors: Holthenrich, Anna, Drexler, Hannes C.A., Chehab, Tarek, Naß, Johannes, Gerke, Volker
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270391/
https://ncbi.nlm.nih.gov/pubmed/31262780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000786
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