Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells

OBJECTIVE—: Endothelial cells store VWF (von Willebrand factor) in rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs). WPB exocytosis is coordinated by a complex network of Rab GTPases, Rab effectors, and SNARE (soluble NSF attachment protein receptor) proteins. We have previously i...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Schillemans, Maaike, Karampini, Ellie, van den Eshof, Bart L., Gangaev, Anastasia, Hofman, Menno, van Breevoort, Dorothee, Meems, Henriët, Janssen, Hans, Mulder, Aat A., Jost, Carolina R., Escher, Johanna C., Adam, Rüdiger, Carter, Tom, Koster, Abraham J., van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Basic Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039413/
https://ncbi.nlm.nih.gov/pubmed/29880488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310701
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