Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells

OBJECTIVE—: Endothelial cells store VWF (von Willebrand factor) in rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs). WPB exocytosis is coordinated by a complex network of Rab GTPases, Rab effectors, and SNARE (soluble NSF attachment protein receptor) proteins. We have previously i...

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Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Schillemans, Maaike, Karampini, Ellie, van den Eshof, Bart L., Gangaev, Anastasia, Hofman, Menno, van Breevoort, Dorothee, Meems, Henriët, Janssen, Hans, Mulder, Aat A., Jost, Carolina R., Escher, Johanna C., Adam, Rüdiger, Carter, Tom, Koster, Abraham J., van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2018
Fag:
Basic Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039413/
https://ncbi.nlm.nih.gov/pubmed/29880488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310701
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