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Sec22b determines Weibel-Palade body length by controlling anterograde endoplasmic reticulum-Golgi transport
Von Willebrand factor (VWF) is a multimeric hemostatic protein that is synthesized in endothelial cells, where it is stored for secretion in elongated secretory organelles called Weibel-Palade bodies (WPB). The hemostatic activity of VWF is strongly related to the length of these bodies, but how end...
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| izdano v: | Haematologica |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Fondazione Ferrata Storti
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8018124/ https://ncbi.nlm.nih.gov/pubmed/32336681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.242727 |
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