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Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cells

Changes in the size of cellular organelles are often linked to modifications in their function. Endothelial cells store von Willebrand Factor (vWF), a glycoprotein essential to haemostasis in Weibel-Palade bodies (WPBs), cigar-shaped secretory granules that are generated in a wide range of sizes. We...

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Vydáno v:Sci Rep
Hlavní autoři: Ferraro, Francesco, Mafalda Lopes da, Silva, Grimes, William, Lee, Hwee Kuan, Ketteler, Robin, Kriston-Vizi, Janos, Cutler, Daniel F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006059/
https://ncbi.nlm.nih.gov/pubmed/27576551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32473
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