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Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cells

Changes in the size of cellular organelles are often linked to modifications in their function. Endothelial cells store von Willebrand Factor (vWF), a glycoprotein essential to haemostasis in Weibel-Palade bodies (WPBs), cigar-shaped secretory granules that are generated in a wide range of sizes. We...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ferraro, Francesco, Mafalda Lopes da, Silva, Grimes, William, Lee, Hwee Kuan, Ketteler, Robin, Kriston-Vizi, Janos, Cutler, Daniel F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006059/
https://ncbi.nlm.nih.gov/pubmed/27576551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32473
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