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Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β(2)-Microglobulin
To form extracellular aggregates, amyloidogenic proteins bypass the intracellular quality control, which normally targets unfolded/aggregated polypeptides. Human D76N β(2)-microglobulin (β(2)m) variant is the prototype of unstable and amyloidogenic protein that forms abundant extracellular fibrillar...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3916536/ https://ncbi.nlm.nih.gov/pubmed/24338476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.524157 |
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