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p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

p53 and tau are both associated with neurodegenerative disorders. Here, we show by Western blotting that p53 is upregulated approximately 2-fold in the superior temporal gyrus of Alzheimer's patients compared to healthy elderly control subjects. Moreover, p53 was found to induce phosphorylation...

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Bibliografische gegevens
Hoofdauteurs: Hooper, Claudie, Meimaridou, Eirini, Tavassoli, Mahvash, Melino, Gerry, Lovestone, Simon, Killick, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Scientific Publishers Ireland 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885960/
https://ncbi.nlm.nih.gov/pubmed/17399897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.03.026
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