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MYPT1 isoforms expressed in HEK293T cells are differentially phosphorylated after GTPγS treatment

Agonist stimulation of smooth muscle is known to activate RhoA/Rho kinase signaling, and Rho kinase phosphorylates the myosin targeting subunit (MYPT1) of myosin light chain (MLC) phosphatase at Thr696 and Thr853, which inhibits the activity of MLC phosphatase to produce a Ca(2+) independent increas...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Smooth Muscle Res
Prif Awduron: Lin, Simon, Brozovich, Frank V
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Japan Society of Smooth Muscle Research 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321854/
https://ncbi.nlm.nih.gov/pubmed/27725371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.52.66
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