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MYPT1 isoforms expressed in HEK293T cells are differentially phosphorylated after GTPγS treatment
Agonist stimulation of smooth muscle is known to activate RhoA/Rho kinase signaling, and Rho kinase phosphorylates the myosin targeting subunit (MYPT1) of myosin light chain (MLC) phosphatase at Thr696 and Thr853, which inhibits the activity of MLC phosphatase to produce a Ca(2+) independent increas...
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| Publicado no: | J Smooth Muscle Res |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Japan Society of Smooth Muscle Research
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321854/ https://ncbi.nlm.nih.gov/pubmed/27725371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.52.66 |
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