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A rapid, PPAR-γ-dependent effect of pioglitazone on the phosphorylation of MYPT

Peroxisome proliferator-activated receptor (PPAR)-γ ligands, thiazolidinediones, have been demonstrated to regulate vascular reactivity. We examined the effect of pioglitazone (PIO; 20 μM) in rat primary cultured aortic smooth muscle cells on constitutive phosphorylation of the regulatory subunit of...

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Detalhes bibliográficos
Main Authors: Atkins, Kevin B., Irey, Brittany, Xiang, Nan, Brosius, Frank C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681377/
https://ncbi.nlm.nih.gov/pubmed/19261909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00343.2008
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