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p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

p53 and tau are both associated with neurodegenerative disorders. Here, we show by Western blotting that p53 is upregulated approximately 2-fold in the superior temporal gyrus of Alzheimer's patients compared to healthy elderly control subjects. Moreover, p53 was found to induce phosphorylation...

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Bibliografski detalji
Glavni autori: Hooper, Claudie, Meimaridou, Eirini, Tavassoli, Mahvash, Melino, Gerry, Lovestone, Simon, Killick, Richard
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Scientific Publishers Ireland 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885960/
https://ncbi.nlm.nih.gov/pubmed/17399897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.03.026
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