p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

p53 and tau are both associated with neurodegenerative disorders. Here, we show by Western blotting that p53 is upregulated approximately 2-fold in the superior temporal gyrus of Alzheimer's patients compared to healthy elderly control subjects. Moreover, p53 was found to induce phosphorylation...

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Detaylı Bibliyografya
Asıl Yazarlar: Hooper, Claudie, Meimaridou, Eirini, Tavassoli, Mahvash, Melino, Gerry, Lovestone, Simon, Killick, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Scientific Publishers Ireland 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885960/
https://ncbi.nlm.nih.gov/pubmed/17399897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.03.026
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