Heterogeneity of Phosphatidylinositol-3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin Activation in Cancer: Is PI3K Isoform Specificity Important?

af Cintas, Célia, Guillermet-Guibert, Julie
Udgivet i Front Oncol (2018)

Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor

af Berenjeno, Inma M., Guillermet-Guibert, Julie, Pearce, Wayne, Gray, Alexander, Fleming, Stewart, Vanhaesebroeck, Bart
Udgivet 2012

Loss of p27(Kip1) promotes metaplasia in the pancreas via the regulation of Sox9 expression

af Jeannot, Pauline, Callot, Caroline, Baer, Romain, Duquesnes, Nicolas, Guerra, Carmen, Guillermet-Guibert, Julie, Bachs, Oriol, Besson, Arnaud
Udgivet i Oncotarget (2015)

Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics

af Cintas, Célia, Douché, Thibaut, Therville, Nicole, Arcucci, Silvia, Ramos-Delgado, Fernanda, Basset, Céline, Thibault, Benoît, Guillermet-Guibert, Julie
Udgivet i Cancers (Basel) (2018)

Experimental pancreatic cancer develops in soft pancreas: novel leads for an individualized diagnosis by ultrafast elasticity imaging

af Therville, Nicole, Arcucci, Silvia, Vertut, Aurélie, Ramos-Delgado, Fernanda, Da Mota, Dina Ferreira, Dufresne, Marlène, Basset, Céline, Guillermet-Guibert, Julie
Udgivet i Theranostics (2019)

Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance

af Le Naour, Augustin, Mevel, Renaud, Thibault, Benoit, Courtais, Elise, Chantalat, Elodie, Delord, Jean Pierre, Couderc, Bettina, Guillermet-Guibert, Julie, Martinez, Alejandra
Udgivet i Oncotarget (2018)

The p110β isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110γ

af Guillermet-Guibert, Julie, Bjorklof, Katja, Salpekar, Ashreena, Gonella, Cristiano, Ramadani, Faruk, Bilancio, Antonio, Meek, Stephen, Smith, Andrew J. H., Okkenhaug, Klaus, Vanhaesebroeck, Bart
Udgivet 2008

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis

af Soler, Adriana, Serra, Helena, Pearce, Wayne, Angulo, Ana, Guillermet-Guibert, Julie, Friedman, Lori S., Viñals, Francesc, Gerhardt, Holger, Casanovas, Oriol, Graupera, Mariona, Vanhaesebroeck, Bart
Udgivet 2013

Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway

af Bousquet, Corinne, Guillermet-Guibert, Julie, Saint-Laurent, Nathalie, Archer-Lahlou, Elodie, Lopez, Frédéric, Fanjul, Marjorie, Ferrand, Audrey, Fourmy, Daniel, Pichereaux, Carole, Monsarrat, Bernard, Pradayrol, Lucien, Estève, Jean-Pierre, Susini, Christiane
Udgivet 2006

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

af Baer, Romain, Cintas, Célia, Dufresne, Marlène, Cassant-Sourdy, Stéphanie, Schönhuber, Nina, Planque, Laetitia, Lulka, Hubert, Couderc, Bettina, Bousquet, Corinne, Garmy-Susini, Barbara, Vanhaesebroeck, Bart, Pyronnet, Stéphane, Saur, Dieter, Guillermet-Guibert, Julie
Udgivet i Genes Dev (2014)

Pancreatic preneoplastic lesions plasma signatures and biomarkers based on proteome profiling of mouse models

af Ligat, Laetitia, Saint-Laurent, Nathalie, El-Mrani, Aïcha, Gigoux, Véronique, Al Saati, Talal, Tomasini, Richard, Nigri, Jérémy, Dejean, Sébastien, Pont, Frédéric, Baer, Romain, Guillermet-Guibert, Julie, Cordelier, Pierre, Lopez, Frédéric, Dufresne, Marlène
Udgivet i Br J Cancer (2015)

Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

af Zamora, Audrey, Alves, Melinda, Chollet, Charlotte, Therville, Nicole, Fougeray, Tiffany, Tatin, Florence, Franchet, Camille, Gomez-Brouchet, Anne, Vaysse, Charlotte, Martinez, Laurent O., Najib, Souad, Guillermet-Guibert, Julie, Lacazette, Eric, Prats, Anne-Catherine, Garmy-Susini, Barbara
Udgivet i Cell Death Dis (2019)

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

af Guillermet-Guibert, Julie, Smith, Lee B., Halet, Guillaume, Whitehead, Maria A., Pearce, Wayne, Rebourcet, Diane, León, Kelly, Crépieux, Pascale, Nock, Gemma, Strömstedt, Maria, Enerback, Malin, Chelala, Claude, Graupera, Mariona, Carroll, John, Cosulich, Sabina, Saunders, Philippa T. K., Huhtaniemi, Ilpo, Vanhaesebroeck, Bart
Udgivet i PLoS Genet (2015)

eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer

af Müller, David, Shin, Sauyeun, Goullet de Rugy, Théo, Samain, Rémi, Baer, Romain, Strehaiano, Manon, Masvidal-Sanz, Laia, Guillermet-Guibert, Julie, Jean, Christine, Tsukumo, Yoshinori, Sonenberg, Nahum, Marion, Frédéric, Guilbaud, Nicolas, Hoffmann, Jean-Sébastien, Larsson, Ola, Bousquet, Corinne, Pyronnet, Stéphane, Martineau, Yvan
Udgivet i JCI Insight (2019)

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

af Al-Qassab, Hind, Smith, Mark A., Irvine, Elaine E., Guillermet-Guibert, Julie, Claret, Marc, Choudhury, Agharul I., Selman, Colin, Piipari, Kaisa, Clements, Melanie, Lingard, Steven, Chandarana, Keval, Bell, Jimmy D., Barsh, Gregory S., Smith, Andrew J.H., Batterham, Rachel L., Ashford, Michael L.J., Vanhaesebroeck, Bart, Withers, Dominic J.
Udgivet 2009

Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component

af Thibault, Benoit, Ramos‐Delgado, Fernanda, Pons‐Tostivint, Elvire, Therville, Nicole, Cintas, Celia, Arcucci, Silvia, Cassant‐Sourdy, Stephanie, Reyes‐Castellanos, Gabriela, Tosolini, Marie, Villard, Amelie V, Cayron, Coralie, Baer, Romain, Bertrand‐Michel, Justine, Pagan, Delphine, Ferreira Da Mota, Dina, Yan, Hongkai, Falcomatà, Chiara, Muscari, Fabrice, Bournet, Barbara, Delord, Jean‐Pierre, Aksoy, Ezra, Carrier, Alice, Cordelier, Pierre, Saur, Dieter, Basset, Celine, Guillermet‐Guibert, Julie
Udgivet i EMBO Mol Med (2021)