Loss of p27(Kip1) promotes metaplasia in the pancreas via the regulation of Sox9 expression

p27(Kip1) (p27) is a negative regulator of proliferation and a tumor suppressor via the inhibition of cyclin-CDK activity in the nucleus. p27 is also involved in the regulation of other cellular processes, including transcription by acting as a transcriptional co-repressor. Loss of p27 expression is...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Jeannot, Pauline, Callot, Caroline, Baer, Romain, Duquesnes, Nicolas, Guerra, Carmen, Guillermet-Guibert, Julie, Bachs, Oriol, Besson, Arnaud
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742148/
https://ncbi.nlm.nih.gov/pubmed/26416424
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