p27(Kip1) promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway

p27(Kip1) (p27) is a cyclin-CDK inhibitor and negative regulator of cell proliferation. p27 also controls other cellular processes including migration and cytoplasmic p27 can act as an oncogene. Furthermore, cytoplasmic p27 promotes invasion and metastasis, in part by promoting epithelial to mesench...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Jeannot, Pauline, Nowosad, Ada, Perchey, Renaud T, Callot, Caroline, Bennana, Evangeline, Katsube, Takanori, Mayeux, Patrick, Guillonneau, François, Manenti, Stéphane, Besson, Arnaud
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2017
Gaiak:
Cancer Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388532/
https://ncbi.nlm.nih.gov/pubmed/28287395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22207
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