p27(Kip1) promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway

p27(Kip1) (p27) is a cyclin-CDK inhibitor and negative regulator of cell proliferation. p27 also controls other cellular processes including migration and cytoplasmic p27 can act as an oncogene. Furthermore, cytoplasmic p27 promotes invasion and metastasis, in part by promoting epithelial to mesench...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Jeannot, Pauline, Nowosad, Ada, Perchey, Renaud T, Callot, Caroline, Bennana, Evangeline, Katsube, Takanori, Mayeux, Patrick, Guillonneau, François, Manenti, Stéphane, Besson, Arnaud
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2017
Ämnen:
Cancer Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388532/
https://ncbi.nlm.nih.gov/pubmed/28287395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22207
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