FAK in cancer: mechanistic findings and clinical applications

Por Sulzmaier, Florian J., Jean, Christine, Schlaepfer, David D.
Publicado no Nat Rev Cancer (2014)

Innate predisposition to immune escape in follicular lymphoma cells

Por Gravelle, Pauline, Jean, Christine, Valleron, Wilfried, Laurent, Guy, Fournié, Jean-Jacques
Publicado em 2012

PKCζ protects against UV-C-induced apoptosis by inhibiting acid sphingomyelinase-dependent ceramide production

Por Charruyer, Alexandra, Jean, Christine, Colomba, Audrey, Jaffrézou, Jean-Pierre, Quillet-Mary, Anne, Laurent, Guy, Bezombes, Christine
Publicado em 2007

FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth

Por Tancioni, Isabelle, Miller, Nichol LG, Uryu, Sean, Lawson, Christine, Jean, Christine, Chen, Xiao Lei, Kleinschmidt, Elizabeth G, Schlaepfer, David D
Publicado no Breast Cancer Res (2015)

FAK inhibition disrupts a β5 integrin signaling axis controlling anchorage-independent ovarian carcinoma growth

Por Tancioni, Isabelle, Uryu, Sean, Sulzmaier, Florian J., Shah, Nina R., Lawson, Christine, Miller, Nichol L.G., Jean, Christine, Chen, Xiao Lei, Ward, Kristy K., Schlaepfer, David D.
Publicado em 2014

Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer

Por Shah, Nina R., Tancioni, Isabelle, Ward, Kristy K., Lawson, Christine, Chen, Xiao Lei, Jean, Christine, Sulzmaier, Florian J., Uryu, Sean, Miller, Nichol L.G., Connolly, Denise C., Schlaepfer, David D.
Publicado em 2014

Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts

Por Moatassim-Billah, Siham, Duluc, Camille, Samain, Rémi, Jean, Christine, Perraud, Aurélie, Decaup, Emilie, Cassant-Sourdy, Stéphanie, Bakri, Youssef, Selves, Janick, Schmid, Herbert, Martineau, Yvan, Mathonnet, Muriel, Pyronnet, Stéphane, Bousquet, Corinne
Publicado no Oncotarget (2016)

Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression

Por Ward, Kristy K., Tancioni, Isabelle, Lawson, Christine, Miller, Nichol L.G., Jean, Christine, Chen, Xiao Lei, Uryu, Sean, Kim, Josephine, Tarin, David, Stupack, Dwayne G., Plaxe, Steven C., Schlaepfer, David D.
Publicado em 2012

Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function

Por Jean, Christine, Chen, Xiao Lei, Nam, Ju-Ock, Tancioni, Isabelle, Uryu, Sean, Lawson, Christine, Ward, Kristy K., Walsh, Colin T., Miller, Nichol L.G., Ghassemian, Majid, Turowski, Patric, Dejana, Elisabetta, Weis, Sara, Cheresh, David A., Schlaepfer, David D.
Publicado em 2014

VEGF-induced vascular permeability is mediated by FAK

Por Chen, Xiao Lei, Nam, Ju-Ock, Jean, Christine, Lawson, Christine, Walsh, Colin T., Goka, Erik, Lim, Ssang-Taek, Tomar, Alok, Tanjoni, Isabelle, Uryu, Sean, Guan, Jun-Lin, Acevedo, Lisette M., Weis, Sara M., Cheresh, David A., Schlaepfer, David D.
Publicado em 2012