Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts

Pancreatic ductal adenocarcinoma (PDA) shows a rich stroma where cancer-associated fibroblasts (CAFs) represent the major cell type. CAFs are master secretors of proteins with pro-tumor features. CAF targeting remains a promising challenge for PDA, a devastating disease where treatments focusing on...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Moatassim-Billah, Siham, Duluc, Camille, Samain, Rémi, Jean, Christine, Perraud, Aurélie, Decaup, Emilie, Cassant-Sourdy, Stéphanie, Bakri, Youssef, Selves, Janick, Schmid, Herbert, Martineau, Yvan, Mathonnet, Muriel, Pyronnet, Stéphane, Bousquet, Corinne
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173080/
https://ncbi.nlm.nih.gov/pubmed/27177087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9296
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