Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression

Recurrence and spread of ovarian cancer is the 5th leading cause of death for women in the United States. Focal adhesion kinase (FAK) is a cytoplasmic protein-tyrosine kinase located on chromosome 8q24.3 (gene is Ptk2), a site commonly amplified in serous ovarian cancer. Elevated FAK mRNA levels in...

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Bibliografiset tiedot
Päätekijät: Ward, Kristy K., Tancioni, Isabelle, Lawson, Christine, Miller, Nichol L.G., Jean, Christine, Chen, Xiao Lei, Uryu, Sean, Kim, Josephine, Tarin, David, Stupack, Dwayne G., Plaxe, Steven C., Schlaepfer, David D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622195/
https://ncbi.nlm.nih.gov/pubmed/23275034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-012-9562-5
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