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A non-canonical role for Rgnef in promoting integrin-stimulated focal adhesion kinase activation
Rgnef (also known as p190RhoGEF or ARHGEF28) is a Rho guanine-nucleotide-exchange factor (GEF) that binds focal adhesion kinase (FAK). FAK is recruited to adhesions and activated by integrin receptors binding to matrix proteins, such as fibronectin (FN). Canonical models place Rgnef downstream of in...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
The Company of Biologists
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820247/ https://ncbi.nlm.nih.gov/pubmed/24006257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.135509 |
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