AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Hypothalamic AMP-activated protein kinase (AMPK) has been suggested to act as a key sensing mechanism, responding to hormones and nutrients in the regulation of energy homeostasis. However, the precise neuronal populations and cellular mechanisms involved are unclear. The effects of long-term manipu...

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Autori principali: Claret, Marc, Smith, Mark A., Batterham, Rachel L., Selman, Colin, Choudhury, Agharul I., Fryer, Lee G.D., Clements, Melanie, Al-Qassab, Hind, Heffron, Helen, Xu, Allison W., Speakman, John R., Barsh, Gregory S., Viollet, Benoit, Vaulont, Sophie, Ashford, Michael L.J., Carling, David, Withers, Dominic J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934578/
https://ncbi.nlm.nih.gov/pubmed/17671657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31516
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