Mammalian models of extended healthy lifespan

von Selman, Colin, Withers, Dominic J.
Veröffentlicht 2011

Physiology: An atypical switch for metabolism and ageing

von Selman, Colin, Withers, Dominic J.
Veröffentlicht in Nature (2017)

Out with the old

von Gil, Jesús, Withers, Dominic J
Veröffentlicht in Nature (2016)

Replication of Extended Lifespan Phenotype in Mice with Deletion of Insulin Receptor Substrate 1

von Selman, Colin, Partridge, Linda, Withers, Dominic J.
Veröffentlicht 2011

Longevity of insulin receptor substrate1 null mice is not associated with increased basal antioxidant protection or reduced oxidative damage

von Page, Melissa M., Withers, Dominic J., Selman, Colin
Veröffentlicht 2012

Bio-informatics analysis of a gene co-expression module in adipose tissue containing the diet-responsive gene Nnat

von Li, Xinzhong, Thomason, Peter A, Withers, Dominic J, Scott, James
Veröffentlicht 2010

Genomic imprinting and its effects on postnatal growth and adult metabolism

von Millership, Steven J., Van de Pette, Mathew, Withers, Dominic J.
Veröffentlicht in Cell Mol Life Sci (2019)

Stat6 and IRS-2 Cooperate in Interleukin 4 (IL-4)-Induced Proliferation and Differentiation but Are Dispensable for IL-4-Dependent Rescue from Apoptosis

von Wurster, Andrea L., Withers, Dominic J., Uchida, Tohru, White, Morris F., Grusby, Michael J.
Veröffentlicht 2002

Metabotyping of Long-Lived Mice using (1)H NMR Spectroscopy

von Wijeyesekera, Anisha, Selman, Colin, Barton, Richard H., Holmes, Elaine, Nicholson, Jeremy K., Withers, Dominic J.
Veröffentlicht in J Proteome Res (2012)

Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

von Page, Melissa M., Schuster, Eugene F., Mudaliar, Manikhandan, Herzyk, Pawel, Withers, Dominic J., Selman, Colin
Veröffentlicht in Aging (Albany NY) (2018)

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress

von Page, Melissa M, Sinclair, Amy, Robb, Ellen L, Stuart, Jeffrey A, Withers, Dominic J, Selman, Colin
Veröffentlicht in Aging Cell (2014)

Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances

von Smith, Mark A, Hisadome, Kazunari, Al-Qassab, Hind, Heffron, Helen, Withers, Dominic J, Ashford, Michael L J
Veröffentlicht 2007

Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice

von Jové, Mariona, Naudí, Alba, Ramírez-Núñez, Omar, Portero-Otín, Manuel, Selman, Colin, Withers, Dominic J, Pamplona, Reinald
Veröffentlicht in Aging Cell (2014)

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice

von Selman, Colin, Sinclair, Amy, Pedroni, Silvia M.A., Irvine, Elaine E., Michie, Alison M., Withers, Dominic J.
Veröffentlicht in Oncotarget (2016)

Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

von Foukas, Lazaros C, Bilanges, Benoit, Bettedi, Lucia, Pearce, Wayne, Ali, Khaled, Sancho, Sara, Withers, Dominic J, Vanhaesebroeck, Bart
Veröffentlicht 2013

Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease

von Irvine, Elaine E., Katsouri, Loukia, Plattner, Florian, Al-Qassab, Hind, Al-Nackkash, Rand, Bates, Gillian P., Withers, Dominic J.
Veröffentlicht in Sci Rep (2019)

Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance

von Chandarana, Keval, Gelegen, Cigdem, Irvine, Elaine E., Choudhury, Agharul I., Amouyal, Chloé, Andreelli, Fabrizio, Withers, Dominic J., Batterham, Rachel L.
Veröffentlicht 2013

Calcium Channel Ca(V)2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons

von Smith, Mark A., Katsouri, Loukia, Virtue, Samuel, Choudhury, Agharul I., Vidal-Puig, Antonio, Ashford, Michael L.J., Withers, Dominic J.
Veröffentlicht in Cell Rep (2018)

Galactose‐modified duocarmycin prodrugs as senolytics

von Guerrero, Ana, Guiho, Romain, Herranz, Nicolás, Uren, Anthony, Withers, Dominic J., Martínez‐Barbera, Juan Pedro, Tietze, Lutz F., Gil, Jesús
Veröffentlicht in Aging Cell (2020)

PINK1 deficiency in β-cells increases basal insulin secretion and improves glucose tolerance in mice

von Deas, Emma, Piipari, Kaisa, Machhada, Asif, Li, Abi, Gutierrez-del-Arroyo, Ana, Withers, Dominic J., Wood, Nicholas W., Abramov, Andrey Y.
Veröffentlicht 2014