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Galactose‐modified duocarmycin prodrugs as senolytics

Senescence is a stable growth arrest that impairs the replication of damaged, old or preneoplastic cells, therefore contributing to tissue homeostasis. Senescent cells accumulate during ageing and are associated with cancer, fibrosis and many age‐related pathologies. Recent evidence suggests that th...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Guerrero, Ana, Guiho, Romain, Herranz, Nicolás, Uren, Anthony, Withers, Dominic J., Martínez‐Barbera, Juan Pedro, Tietze, Lutz F., Gil, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189988/
https://ncbi.nlm.nih.gov/pubmed/32175667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13133
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