Galactose‐modified duocarmycin prodrugs as senolytics

Senescence is a stable growth arrest that impairs the replication of damaged, old or preneoplastic cells, therefore contributing to tissue homeostasis. Senescent cells accumulate during ageing and are associated with cancer, fibrosis and many age‐related pathologies. Recent evidence suggests that th...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Guerrero, Ana, Guiho, Romain, Herranz, Nicolás, Uren, Anthony, Withers, Dominic J., Martínez‐Barbera, Juan Pedro, Tietze, Lutz F., Gil, Jesús
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Original Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189988/
https://ncbi.nlm.nih.gov/pubmed/32175667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13133
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