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A five-membered lactone prodrug of CBI-based analogs of the duocarmycins
The preparation, characterization and examination of the CBI-based 5-membered lactone 5 capable of serving as a prodrug or protein (antibody) conjugation reagent are disclosed along with its incorporation into the corresponding CC-1065 and duocarmycin analog 6, and the establishment of their propert...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4459655/ https://ncbi.nlm.nih.gov/pubmed/26069351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.11.038 |
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