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Synthesis and evaluation of a series of C5’-substituted duocarmycin SA analogs

The synthesis and evaluation of a key series of analogs of duocarmycin SA, bearing a single substituent at the C5’ position of the DNA binding subunit, are described.

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Bibliografske podrobnosti
Main Authors: Robertson, William M., Kastrinsky, David B., Hwang, Inkyu, Boger, Dale L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867475/
https://ncbi.nlm.nih.gov/pubmed/20381346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.03.078
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