The N-terminal adenosine triphosphate binding domain of Hsp90 is necessary and sufficient for interaction with estrogen receptor

Por Bouhouche-Chatelier, Ilham, Chadli, Ahmed, Catelli, Maria-Grazia
Publicado em 2001

GCUNC45 Is the First Hsp90 Co-chaperone to Show α/β Isoform Specificity

Por Chadli, Ahmed, Felts, Sara J., Toft, David O.
Publicado em 2008

Progesterone receptor chaperone complex-based highthroughput screening assay: identification of capsaicin as inhibitor of Hsp90 machine

Por Patwardhan, Chaitanya A., Alfa, Eyad, Lu, Su, Chadli, Ahmed
Publicado no J Biomol Screen (2014)

UNC45A localizes to centrosomes and regulates cancer cell proliferation through ChK1 activation

Por Jilani, Yasmeen, Lu, Su, Lei, Huang, Karnitz, Larry M., Chadli, Ahmed
Publicado no Cancer Lett (2014)

Hsp90 Regulates NADPH Oxidase Activity and Is Necessary for Superoxide but Not Hydrogen Peroxide Production

Por Chen, Feng, Pandey, Deepesh, Chadli, Ahmed, Catravas, John D., Chen, Teng, Fulton, David J.R.
Publicado em 2011

Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis

Por Patwardhan, Chaitanya A., Fauq, Abdul, Peterson, Laura B., Miller, Charles, Blagg, Brian S. J., Chadli, Ahmed
Publicado em 2013

Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition

Por Poole, Candace J., Zheng, Wenli, Lee, Haesung, Young, Danielle, Lodh, Atul, Chadli, Ahmed, van Riggelen, Jan
Publicado no Cancers (Basel) (2018)

Dimerization and N-terminal domain proximity underlie the function of the molecular chaperone heat shock protein 90

Por Chadli, Ahmed, Bouhouche, Ilham, Sullivan, William, Stensgard, Bridget, McMahon, Nancy, Catelli, Maria G., Toft, David O.
Publicado em 2000

Adenosine Kinase Inhibition Protects The Kidney Against Streptozotocin-Induced Diabetes Through Anti-inflammatory and Anti-oxidant Mechanisms

Por Pye, Chelsey, Elsherbiny, Nehal M., Ibrahim, Ahmed S., Liou, Gregory I., Chadli, Ahmed, Al-Shabrawey, Mohamed, Elmarakby, Ahmed A.
Publicado no Pharmacol Res (2014)

The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter

Por Kang, Kwang Il, Meng, Xia, Devin-Leclerc, Jocelyne, Bouhouche, Ilham, Chadli, Ahmed, Cadepond, Françoise, Baulieu, Etienne-Emile, Catelli, Maria-Grazia
Publicado em 1999

Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

Por Chadli, Ahmed, Felts, Sara J., Wang, Qin, Sullivan, William P., Botuyan, Maria Victoria, Fauq, Abdul, Ramirez-Alvarado, Marina, Mer, Georges
Publicado em 2010

Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity

Por Lemos, Henrique, Ou, Rong, McCardle, Caroline, Lin, Yijun, Calver, Jessica, Minett, Jack, Chadli, Ahmed, Huang, Lei, Mellor, Andrew L
Publicado no J Immunother Cancer (2020)

GCUNC-45 Is a Novel Regulator for the Progesterone Receptor/hsp90 Chaperoning Pathway

Por Chadli, Ahmed, Graham, J. Dinny, Abel, M. Greg, Jackson, Twila A., Gordon, David F., Wood, William M., Felts, Sara J., Horwitz, Kathryn B., Toft, David
Publicado em 2006

Bioactive Metabolites from Chaetomium aureum: Structure Elucidation and Inhibition of the Hsp90 Machine Chaperoning Activity

Por Kabbaj, Fatima Zahra, Lu, Su, Faouzi, My El Abbés, Meddah, Bouchra, Proksch, Peter, Cherrah, Yahya, Altenbach, Hans-Josef, Aly, Amal H., Chadli, Ahmed, Debbab, Abdessamad
Publicado no Bioorg Med Chem (2014)

The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20

Por Lee, Eunmi, Ouzounova, Maria, Piranlioglu, Raziye, Ma, Minh Thu, Guzel, Mustafa, Marasco, Daniela, Chadli, Ahmed, Gestwicki, Jason E., Cowell, John K., Wicha, Max S., Hassan, Khaled A., Korkaya, Hasan
Publicado no Oncogene (2018)

Opposing Actions of Heat Shock Protein 90 and 70 Regulate Nicotinamide Adenine Dinucleotide Phosphate Oxidase Stability and Reactive Oxygen Species Production

Por Chen, Feng, Yu, Yanfang, Qian, Jin, Wang, Yusi, Cheng, Bo, Dimitropoulou, Christiana, Patel, Vijay, Chadli, Ahmed, Rudic, R. Dan, Stepp, David W., Catravas, John D., Fulton, David J.R.
Publicado em 2012

The Cochaperone SGTA (Small Glutamine-rich Tetratricopeptide Repeat-containing Protein Alpha) Demonstrates Regulatory Specificity for the Androgen, Glucocorticoid, and Progesterone...

Por Paul, Atanu, Garcia, Yenni A., Zierer, Bettina, Patwardhan, Chaitanya, Gutierrez, Omar, Hildenbrand, Zacariah, Harris, Diondra C., Balsiger, Heather A., Sivils, Jeffrey C., Johnson, Jill L., Buchner, Johannes, Chadli, Ahmed, Cox, Marc B.
Publicado em 2014

Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

Por Ouzounova, Maria, Lee, Eunmi, Piranlioglu, Raziye, El Andaloussi, Abdeljabar, Kolhe, Ravindra, Demirci, Mehmet F., Marasco, Daniela, Asm, Iskander, Chadli, Ahmed, Hassan, Khaled A., Thangaraju, Muthusamy, Zhou, Gang, Arbab, Ali S., Cowell, John K., Korkaya, Hasan
Publicado no Nat Commun (2017)

Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

Por Piranlioglu, Raziye, Lee, EunMi, Ouzounova, Maria, Bollag, Roni J., Vinyard, Alicia H., Arbab, Ali S., Marasco, Daniela, Guzel, Mustafa, Cowell, John K., Thangaraju, Muthushamy, Chadli, Ahmed, Hassan, Khaled A., Wicha, Max S., Celis, Esteban, Korkaya, Hasan
Publicado no Nat Commun (2019)

Nox5 Stability and Superoxide Production is Regulated by C-terminal Binding of Hsp90 and Co-Chaperones

Por Chen, Feng, Haigh, Steven, Yu, Yanfang, Benson, Tyler, Wang, Yusi, Li, Xueyi, Dou, Huijuan, Bagi, Zsolt, Verin, Alexander D., Stepp, David W., Csanyi, Gabor, Chadli, Ahmed, Weintraub, Neal L., Smith, Susan M. E., Fulton, David J.R.
Publicado no Free Radic Biol Med (2015)