Bioactive Metabolites from Chaetomium aureum: Structure Elucidation and Inhibition of the Hsp90 Machine Chaperoning Activity

Chemical investigation of the EtOAc extract of the fungus Chaetomium aureum, an endophyte of the Moroccan medicinal plant Thymelaea lythroides, afforded one new resorcinol derivative named chaetorcinol, together with five known metabolites. The structures of the isolated compounds were determined on...

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Pubblicato in:Bioorg Med Chem
Autori principali: Kabbaj, Fatima Zahra, Lu, Su, Faouzi, My El Abbés, Meddah, Bouchra, Proksch, Peter, Cherrah, Yahya, Altenbach, Hans-Josef, Aly, Amal H., Chadli, Ahmed, Debbab, Abdessamad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274242/
https://ncbi.nlm.nih.gov/pubmed/25482429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.11.021
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