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Hsp110 Chaperones Control Client Fate Determination in the Hsp70–Hsp90 Chaperone System

Heat shock protein 70 (Hsp70) plays a central role in protein homeostasis and quality control in conjunction with other chaperone machines, including Hsp90. The Hsp110 chaperone Sse1 promotes Hsp90 activity in yeast, and functions as a nucleotide exchange factor (NEF) for cytosolic Hsp70, but the pr...

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Detalhes bibliográficos
Main Authors: Mandal, Atin K., Gibney, Patrick A., Nillegoda, Nadinath B., Theodoraki, Maria A., Caplan, Avrom J., Morano, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861604/
https://ncbi.nlm.nih.gov/pubmed/20237159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0779
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