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Characterization of Hsp70 binding and nucleotide exchange by the yeast Hsp110 chaperone Sse1

SSE1 and SSE2 encode the essential yeast members of the Hsp70-related Hsp110 molecular chaperone family. Both mammalian Hsp110 and the Sse proteins functionally interact with cognate cytosolic Hsp70s as nucleotide exchange factors. We demonstrate here that Sse1 forms high affinity (K(d)~10(−8) M) he...

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Detalhes bibliográficos
Main Authors: Shaner, Lance, Sousa, Rui, Morano, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676923/
https://ncbi.nlm.nih.gov/pubmed/17154545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061279k
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