Adenosine Kinase Inhibition Protects The Kidney Against Streptozotocin-Induced Diabetes Through Anti-inflammatory and Anti-oxidant Mechanisms

Adenosine provides anti-inflammatory effects in cardiovascular disease via the activation of adenosine A(2A) receptors; however, the physiological effect of adenosine could be limited due to its phosphorylation by adenosine kinase. We hypothesized that inhibition of adenosine kinase exacerbates extr...

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Опубликовано в: :Pharmacol Res
Главные авторы: Pye, Chelsey, Elsherbiny, Nehal M., Ibrahim, Ahmed S., Liou, Gregory I., Chadli, Ahmed, Al-Shabrawey, Mohamed, Elmarakby, Ahmed A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302753/
https://ncbi.nlm.nih.gov/pubmed/24841126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2014.05.004
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