Adenosine Deaminase-2–Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p

PURPOSE: We recently demonstrated that adenosine deaminase-2 (ADA2) contributes to diabetic retinopathy (DR) via up-regulating the production of inflammatory cytokines in macrophages. Also, microRNA (miR)-146b-3p has the ability to inhibit ADA2. The goal of this study was to investigate the potentia...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Samra, Yara A., Saleh, Heba M., Hussein, Khaled A., Elsherbiny, Nehal M., Ibrahim, Ahmed S., Elmasry, Khaled, Fulzele, Sadanand, El-Shishtawy, Mamdouh M., Eissa, Laila A., Al-Shabrawey, Mohamed, Liou, Gregory I.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2017
Fag:
Retinal Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300249/
https://ncbi.nlm.nih.gov/pubmed/28170537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19782
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