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Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition

Overexpression of the MYC oncogene is a key feature of many human malignancies including Burkitt lymphoma. While MYC is widely regarded to be a promising therapeutic target, a clinically effective MYC inhibitor is still elusive. Here, we report an alternative strategy, targeting MYC indirectly throu...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Poole, Candace J., Zheng, Wenli, Lee, Haesung, Young, Danielle, Lodh, Atul, Chadli, Ahmed, van Riggelen, Jan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266960/
https://ncbi.nlm.nih.gov/pubmed/30453475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10110448
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