MYC—Master Regulator of the Cancer Epigenome and Transcriptome

Por Poole, Candace J., van Riggelen, Jan
Publicado no Genes (Basel) (2017)

Disturbance of Tumor Necrosis Factor Alpha-Mediated Beta Interferon Signaling in Cervical Carcinoma Cells

Por Bachmann, Anastasia, Hanke, Brigitte, Zawatzky, Rainer, Soto, Ubaldo, van Riggelen, Jan, zur Hausen, Harald, Rösl, Frank
Publicado em 2002

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation

Por Wu, Chi-Hwa, van Riggelen, Jan, Yetil, Alper, Fan, Alice C., Bachireddy, Pavan, Felsher, Dean W.
Publicado em 2007

DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt’s lymphoma

Por Poole, Candace J., Zheng, Wenli, Lodh, Atul, Yevtodiyenko, Aleksey, Liefwalker, Daniel, Li, Honglin, Felsher, Dean W., van Riggelen, Jan
Publicado no Oncotarget (2017)

Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction

Por Choi, Peter S., van Riggelen, Jan, Gentles, Andrew J., Bachireddy, Pavan, Rakhra, Kavya, Adam, Stacey J., Plevritis, Sylvia K., Felsher, Dean W.
Publicado em 2011

The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance

Por van Riggelen, Jan, Müller, Judith, Otto, Tobias, Beuger, Vincent, Yetil, Alper, Choi, Peter S., Kosan, Christian, Möröy, Tarik, Felsher, Dean W., Eilers, Martin
Publicado em 2010

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia

Por Yetil, Alper, Anchang, Benedict, Gouw, Arvin M., Adam, Stacey J., Zabuawala, Tahera, Parameswaran, Ramya, van Riggelen, Jan, Plevritis, Sylvia, Felsher, Dean W.
Publicado no Oncotarget (2015)

High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation(,)

Por Wu, Angela R., Kawahara, Tiara L.A., Rapicavoli, Nicole A., van Riggelen, Jan, Shroff, Emelyn H., Xu, Liwen, Felsher, Dean W., Chang, Howard Y., Quake, Stephen R.
Publicado em 2012

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch

Por Giuriato, Sylvie, Ryeom, Sandra, Fan, Alice C., Bachireddy, Pavan, Lynch, Ryan C., Rioth, Matthew J., van Riggelen, Jan, Kopelman, Andrew M., Passegué, Emmanuelle, Tang, Flora, Folkman, Judah, Felsher, Dean W.
Publicado em 2006