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Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction

The suppression of oncogenic levels of MYC is sufficient to induce sustained tumor regression associated with proliferative arrest, differentiation, cellular senescence, and/or apoptosis, a phenomenon known as oncogene addiction. However, after prolonged inactivation of MYC in a conditional transgen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Choi, Peter S., van Riggelen, Jan, Gentles, Andrew J., Bachireddy, Pavan, Rakhra, Kavya, Adam, Stacey J., Plevritis, Sylvia K., Felsher, Dean W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198348/
https://ncbi.nlm.nih.gov/pubmed/21969595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107303108
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