Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction

The suppression of oncogenic levels of MYC is sufficient to induce sustained tumor regression associated with proliferative arrest, differentiation, cellular senescence, and/or apoptosis, a phenomenon known as oncogene addiction. However, after prolonged inactivation of MYC in a conditional transgen...

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Главные авторы: Choi, Peter S., van Riggelen, Jan, Gentles, Andrew J., Bachireddy, Pavan, Rakhra, Kavya, Adam, Stacey J., Plevritis, Sylvia K., Felsher, Dean W.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198348/
https://ncbi.nlm.nih.gov/pubmed/21969595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107303108
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